The Stellate Ganglion Block (SGB) is an advanced procedure that targets a nerve cluster in the neck to alleviate pain and reduce stress. Initially used for chronic pain management, it is now gaining recognition as a treatment for PTSD, anxiety, and other stress-related conditions.
SGB involves a precise injection of a local anesthetic near the stellate ganglion, a nerve bundle in the neck. This temporarily blocks pain signals and regulates the sympathetic nervous system, providing fast relief from chronic pain and easing symptoms of anxiety and PTSD.
Many patients experience relief shortly after the procedure.
Helps manage chronic pain effectively.
May ease symptoms of PTSD and stress-related conditions.
A minimally invasive procedure with a short recovery time.
Possible side effects include:
A comprehensive evaluation helps determine if SGB is the right choice for you.
A thorough evaluation to determine if SGB is the right fit.
A precise injection near the stellate ganglion using imaging guidance.
Patients are monitored for response and any side effects.
Follow-up visits to assess results and plan further treatment if needed.
Stellate Ganglion Block (SGB) is a minimally invasive injection that targets a group of nerves in the neck involved in the body’s fight-or-flight response. It may help regulate the sympathetic nervous system and is being explored for conditions related to trauma and chronic stress. SGB may help support relief for:
A Stellate Ganglion Block is an injection of local anesthetic near a bundle of nerves in the neck called the stellate ganglion. These nerves influence the body’s sympathetic nervous system, which regulates the fight-or-flight response.
SGB is thought to temporarily “reset” overactivity in the sympathetic nervous system. Some individuals with PTSD experience reduced hyperarousal and improved emotional regulation following treatment.
The injection itself usually takes just a few minutes, and the full appointment typically lasts 30–60 minutes including preparation and monitoring.
Most patients report only mild discomfort. A local anesthetic is used, and the procedure is performed under image guidance for precision and safety.
When performed by trained medical professionals using imaging guidance, SGB is generally considered safe and well tolerated.
The duration of benefits varies. Some individuals experience relief for weeks or months, while others may require additional treatments.
Some patients report changes in symptoms within hours or days, while others may notice improvements gradually over the following weeks.
Patients often have questions about:
Conditions treated at SoCal Infusions
What to expect during infusion therapy
Safety and medical supervision
Appointment scheduling and clinic hours
Location and accessibility
Payment options and financing
SoCal Infusions (Southern California Infusion Therapy) is a Pasadena-based clinic specializing in ketamine infusions and advanced infusion therapies for treatment-resistant depression, anxiety, PTSD, OCD, and chronic pain conditions.
SoCal Infusions uses ketamine to help adults with complex mood and pain conditions, including major depression, anxiety disorders, suicidal ideation, PTSD, OCD, complex regional pain syndrome (CRPS), neuropathic pain, migraines, fibromyalgia, restless leg syndrome, and select postpartum mood symptoms.
Patients begin with a medical evaluation. If ketamine is appropriate, the anesthesiology-led team creates a personalized infusion plan—typically a series of IV treatments delivered in a monitored, spa-like setting. Symptoms are closely tracked, and treatment plans are adjusted as needed.
In many cases, no referral is required, but a professional diagnosis of some sort IS needed to begin the process. We can contact your existing care team to request information.
The clinic is located at 301 S Fair Oaks Ave, Suite 301, Pasadena, CA, in a medical office building near major streets and local hospitals. It is convenient for patients from Pasadena, South Pasadena, and surrounding communities.
Appointments are typically available Monday through Friday from 9:00 a.m. to 5:00 p.m., and Saturdays from 8:00 a.m. to 2:00 p.m.
Good candidates are typically adults with depression, anxiety, PTSD, or chronic pain who have not responded well to standard treatments. The medical team reviews your health history, medications, and current symptoms to determine whether ketamine is a safe and appropriate option.
Southern California Infusion Therapy offers the latest in innovative new treatments for chronic pain and mood disorders such as depression, anxiety, PTSD and OCD.
Copyright © 2026 SoCal Infusions | SoCal Infusions provides medical and mental health services under the supervision of licensed healthcare providers. The information on this website is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider with questions regarding your condition or care. Some treatments offered may be used off-label.
If you are experiencing an emergency, call 911 immediately. If you are in crisis or having suicidal thoughts, call 988 or 1-800-273-TALK (8255).